Pharmaceutical giant Merck is strategically reorienting its global research and development (R&D) operations, opting to consolidate future R&D primarily within the United States while phasing out its London-based activities. This significant realignment highlights a broader industry trend, influenced by divergent government policies and economic incentives across key markets, particularly impacting the life sciences sector.
Merck’s decision to exit the UK, confirmed on Wednesday, stems from what the company describes as a challenging business environment. Merck specifically cited the United Kingdom’s perceived lack of investment in its life science industry and consistent undervaluation of innovative medicines and vaccines by successive UK governments. Consequently, Merck will abandon plans for a new King’s Cross site, originally slated for 2027, and vacate existing laboratories at the London Bioscience Innovation Centre and the Francis Crick Institute by late 2025. This move is expected to impact approximately 125 staff members.
U.S. Strategic Investment Escalates
The relocation of these R&D functions aligns with a wider pharmaceutical industry trend of escalating investment in the United States. This surge has been partly influenced by the Trump administration’s policies, including tariff threats and consistent pressure on pharmaceutical companies to bolster domestic manufacturing and research capabilities.
Merck itself has made substantial commitments, announcing approximately $9 billion in U.S. investments through 2028. Noteworthy projects include a $1 billion facility in Delaware dedicated to producing biologics and its blockbuster cancer drug Keytruda, projected to create over 4,500 jobs and become operational by 2028. This complements a $1 billion facility opened in North Carolina in March, alongside an $895 million expansion for its Kansas animal health manufacturing and R&D operations.

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